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Medication Class Interaction Effect Notes
Nitrates Severe drop in blood pressure Contraindicated
Alpha-blockers Additive hypotensive effect Use with caution
Other PDE5 inhibitors Increased risk of side effects Avoid combination
CYP3A4 inhibitors Increased tadalafil levels Dose adjustment needed

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Storage Condition Temperature Light Sensitivity Shelf Life Special Instructions
Cool, dry place Below 25°C Yes 2 years Keep out of reach of children
Away from sunlight Room temperature No 2 years Store in original container
Avoid humidity 15-30°C Yes 2 years Do not freeze

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Side Effect Frequency Severity Notes
Headache Common Mild to moderate Usually transient
Flushing Common Mild Due to vasodilation
Nasal Congestion Common Mild Usually temporary
Back Pain Less common Mild Typically subsides
Muscle Pain Less common Mild After intake

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